Predicting the epilepsy surgery, the conversion of magnetic resonance spectroscopy is useful.

Release date: 2006-11-02

Magnetic resonance spectroscopy (MRS) has proven to be a valuable tool in the pre-surgical evaluation of epilepsy. A meta-analysis conducted by Willmann and colleagues at the University Hospital in Mannheim, Germany, highlights the potential of 1H MRS in identifying epileptogenic foci before surgery. The study was published online on August 3, 2006, in *Epilepsy Research*.

The analysis included 22 studies published between 1992 and 2003, all focusing on patients with refractory temporal lobe epilepsy. However, there was significant variability in study design, techniques used, and how data were interpreted. Despite this, the results showed promising trends.

According to the findings, 64% of patients had ipsilateral MRS abnormalities corresponding to the epileptogenic focus, while 72% of those who had favorable surgical outcomes also showed similar findings. The positive predictive value for good outcomes based on ipsilateral MRS abnormalities was 82%. Patients with unilateral MRS abnormalities had a significantly higher chance of being seizure-free post-surgery compared to those with bilateral abnormalities (OR=4.891).

While the researchers acknowledge that MRS is still primarily a research tool, they emphasize its clinical potential. The study suggests that when MRS detects an abnormality consistent with the epileptogenic zone, it may serve as a useful predictor of surgical success. However, further prospective studies are needed, particularly in patients with MRI-negative or EEG-characterized non-localized epilepsy.

—— Information from: China Medical Tribune

Food Additive Monosodium Glutamate 98%

Cheap Food Additives,Good Food Additive,Food Additive Bha,Additive Monosodium Glutamate

JILIN COFCO BIO-CHEM AND BIO-ENERGY MARKETING CO., LTD , https://www.cofco-biotech.com