US researchers have discovered two new compounds that help treat diabetes
Release date: 2006-09-22
In a groundbreaking study, U.S. researchers have identified two promising compounds that could significantly impact the treatment of diabetes. A team from the Harvard T.H. Chan School of Public Health discovered that PBA (4-phenylbutyric acid) and TUDCA (tauroursodeoxycholic acid) show great potential in managing the condition. These compounds were found to restore normal glucose levels and improve insulin function in obese and diabetic mice. Additionally, they help reduce the risk of fatty liver disease, a common complication associated with metabolic disorders.
Currently, PBA is already undergoing clinical trials for urea cycle disorders in humans, as approved by the U.S. Food and Drug Administration (FDA). Meanwhile, TUDCA has been used as a preventive treatment for cholesterol-related liver diseases in people. Researchers believe that these findings may open new doors for diabetes therapies, offering hope for more effective and targeted treatments in the future. As more studies are conducted, the potential applications of these compounds could expand, benefiting patients worldwide. China Medicine 123 Network
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Natural extracts are biologically active compounds or mixtures extracted from various plants and animals or microorganisms in nature. These extracts contain a wealth of chemicals, Such as alkaloids, flavonoids, saponins, polysaccharides, volatile oils, collagen, proteins, peptides, enzymes, antibodies, antibiotics, Amino Acids, nucleic acids, enzymes, monosaccharides, oligosaccharides, polysaccharides, glycoproteins, resins, colloids, lignin, vitamins, fats, oils, waxes, alkaloids, volatile oils, flavonoids, glycosides, phenylpropanoids, organic acids, phenols, quinones, steroids And antibiotics, etc.
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Extraction methods include solvent extraction method, ultrasonic extraction method, microwave extraction method, enzyme extraction method, supercritical fluid extraction method and microwave assisted extraction method, etc. The choice of which method usually depends on the nature of the substance to be extracted and the target requirements of the final product. With the development of technology, the extraction process is continuously optimized to improve extraction efficiency, reduce environmental impact and maintain the biological activity of the extract.
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