Expression CMS : Mass spectrometer with unrivaled versatility

The Advion expressión® Compact Mass Spectrometer (CMS) stands out for its unmatched versatility in sample handling. It supports a range of techniques, from push-button analysis of TLC plates using the Plate Express® system to direct analysis of both solids and liquids with the Atmospheric Solids Analysis Probes (ASAP®). These features make it an ideal tool for chemists who need to quickly assess reaction conditions without extensive sample preparation. Designed with adaptability in mind, the expressión® CMS simplifies the process of switching between various sample introduction methods, transitioning seamlessly from straightforward direct probe analysis to advanced techniques like ultra-high-performance liquid chromatography (UHPLC) and preparative-scale purification. This flexibility ensures that chemists can efficiently address diverse analytical challenges within their workflows. Equipped with interchangeable accessories, the CMS expressión® becomes a highly accessible instrument for any lab. Its ability to effortlessly switch between electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) sources is particularly noteworthy. Unlike other systems where the choice of ionization method is fixed, this mass spectrometer empowers users to select the most appropriate technique based on the compound being analyzed. Transitioning between these modes is straightforward, taking only moments to swap out the source block. Another standout feature is the Plate Express system, which revolutionizes the identification of spots on thin-layer chromatography (TLC) plates. Traditionally, identifying a specific spot involves labor-intensive steps such as scraping the plate, dissolving the sample, and filtering it—all of which can be streamlined with this automated solution. With just a few clicks, the Plate Express extracts the desired spot and delivers it to the CMS expressión® spectrometer, providing results within minutes. For direct analysis of solid or liquid samples, the ASAP® source proves invaluable. Chemists can swiftly analyze materials like reaction mixtures, food samples, and natural products by introducing them directly into the APCI source via a glass capillary. The immediate feedback facilitates rapid decision-making during experiments. When dealing with air-sensitive compounds, the iASAP variant offers protection against environmental exposure through an inert gas enclosure, ensuring samples remain uncontaminated from initial sampling until they reach the mass spectrometer. Innovative solutions like the Touch Express coupled with an Open Port interface cater specifically to those needing both ESI and APCI capabilities. This setup uses a solvent-formed meniscus to deposit and transfer samples, enabling efficient analysis while supporting direct surface studies. Volatile compound analysis benefits from a specialized APCI source equipped with a heated transfer line, allowing headspace sampling directly from vials before directing samples to the CMS expression detector. The CMS expression mass spectrometer also integrates smoothly with (U)HPLC chains, enhancing its utility across multiple applications. Furthermore, when paired with puriFlash® purification systems, it enables targeted compound collection based on mass, eliminating the need for post-collection analysis and streamlining workflows. Versatility, compact design, and user-friendly operation collectively position the CMS expressión® as an essential asset in modern laboratories. Whether you're working with complex mixtures or requiring precise measurements, this instrument meets the demands of contemporary research environments. If you'd like to learn more about how the CMS expressión® can enhance your lab's capabilities, feel free to reach out—we’re happy to assist! Additionally, if you missed our recent presentation at Analytica virtual, explore our puriFlash 360° LC Purification Platform today! [Image descriptions omitted for brevity but could include detailed captions highlighting key components and functionalities mentioned above.]

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