Gene therapy nanofilm
Release date: 2007-04-11
Gene Therapy Nanofilm
Recently, a research team led by Dr. David M. Lynn from the University of Wisconsin in the United States has developed an innovative nano-film technology that could significantly improve the delivery of genetic materials during gene therapy. This new tool is designed to encapsulate DNA along with water-soluble polymers, allowing for a controlled and gradual release of the genetic material into surrounding tissues.
The researchers tested the film by incorporating it into implantable medical devices, such as vascular stents. When applied to these devices, the nano-film can slowly release its contents into the bloodstream, reducing the risk of inflammatory reactions or unwanted blood clotting. According to the scientists involved, the success of this technology relies heavily on the polymer coating used. The nano-film must be thin enough to ensure the slow release of short-chain therapeutic DNA, while also being adaptable for various medical applications. Future research will focus on refining the design to make the coatings more versatile and widely applicable.
Gene therapy involves introducing functional genes into target cells to correct genetic defects or treat diseases at their source. Unlike traditional treatments that manage symptoms, gene therapy aims to address the root cause—the faulty gene itself. Scientists hope that this approach may one day reduce the need for conventional drugs, offering a more direct and long-term solution to genetic disorders. This breakthrough in nanofilm technology represents a significant step forward in the field of gene therapy and could open up new possibilities for treating a wide range of genetic conditions.
Source: Shanghai Medical Devices
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