Ultrasound-assisted extraction of total flavonoids from Lonicera japonica Thunb. and its antioxidant activity in vitro
Lonicera japonica L. is a dry stem of Lonicera japonica L., which is widely distributed. Lonicera japonica and honeysuckle are different medicinal parts of Lonicera japonica L., which are contained in the 2010 edition of the Chinese Pharmacopoeia. Honeysuckle vine is sweet, cold, with heat and detoxification, and the effect of Tongluo. For fever, fever, sore swollen poison, hot poisonous blood stasis, rheumatic fever. Modern research shows that Lonicera japonica has pharmacological effects such as antiviral, anti-inflammatory, anti-tumor and immune regulation.
Lonicera japonica L. is rich in flavonoids, and flavonoids have a variety of pharmacological functions. However, there are no reports on the extraction and in vitro antioxidant activity of total flavonoids from Lonicera japonica Thunb. For the first time, this study optimized the extraction process of total flavonoids from Lonicera japonica Thunb. by central composite experiment. The DPPH free radical scavenging power, ABTS+ free radical scavenging force, Fe2+ chelation force and iron ion reduction antioxidant capacity were used as indicators to detect Lonicera japonica Thunb. In vitro antioxidant activity of total flavonoids. This study provides an experimental basis for the industrial extraction and further development of total flavonoids of Lonicera japonica Thunb.
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